This pattern has caused connection pool exhaustion in Node.js applications using undici (the fetch() implementation built into Node.js), and similar issues have appeared in other runtimes. The stream holds a reference to the underlying connection, and without explicit consumption or cancellation, the connection may linger until garbage collection – which may not happen soon enough under load.
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Lovell retired from the navy in 1973 and opted for a the quiet life, working for the Bay-Houston Towing Company, giving speeches and serving as president of the National Eagle Scout Association.
"There was a lot of controversy about when it first opened, so I was really nervous at first," she said.
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Infigratinib靶向的FGFR3（成纤维细胞生长因子受体3）正是驱动ACH疾病发生的关键靶点，2月12日，BridgeBio公布Infigratinib在ACH中取得的首个具有统计学显著改善意义的3期顶线结果，公司计划下半年向FDA提交新药申请。
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